Fraunhofer IPA
At present, it is not possible to conduct patient-specific analyses of the function and effectiveness of implants in clinical trials. However, there is a solution to this problem in the form of verified and validated (V&V) in-silico analyses of patients together with the implant. This requires smart virtual processes from medical image capture and analysis, as well as biomechanical experiments, in-silico human simulations and CAE (computer-aided engineering) for products. Companies do not currently have these options available, however. An in-silico implant analysis on a large number of patients (> 100) in compliance with regulations can be carried out under realistic physiological and biomechanical conditions at a fraction of the time and cost associated with clinical implant trials. Another advantage of in-silico studies is that new and detailed insights into dynamic interactions between the implant and patient can be obtained from the complex simulations.